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Applications of deep eutectic solvents to quantitative analyses of pharmaceuticals and pesticides in various matrices: a brief review

Archives of Pharmacal Research 2020년 43권 9호 p.900 ~ 919
이정미, 김희림, 강슬기, 백남욱, 황인선, 정두수,
소속 상세정보
이정미 ( Lee Jeong-Mi ) - Sungkyunkwan University School of Pharmacy
김희림 ( Kim Hi-Reem ) - Sungkyunkwan University School of Pharmacy
강슬기 ( Kang Seul-Gi ) - Sungkyunkwan University School of Pharmacy
백남욱 ( Baik Nam-Wook ) - Sungkyunkwan University School of Pharmacy
황인선 ( Hwang In-Seon ) - Sungkyunkwan University School of Pharmacy
정두수 ( Chung Doo-Soo ) - Seoul National University Department of Chemistry

Abstract


Pharmaceuticals and pesticides are important analytes of interest in clinical, environmental, and food analyses for ensuring public health. Sample pretreatment steps are often prerequisites for the quantitative analysis of these compounds, which are generally present in low concentrations in samples with complex matrices. In compliance with the current trend towards green analytical chemistry, the replacement of conventional toxic organic solvents with ecofriendly and safe solvents has been pursued in developing sample pretreatment methods. Subsequent to several reports in 2017, deep eutectic solvents (DESs) have been increasingly applied as desirable alternative solvents in numerous types of sample pretreatment methods for the analysis of pharmaceuticals and pesticides. The present review summarizes analytical methods involving DESs as extraction solvents and as the reaction media or functional materials for preparing adsorbents to quantify pharmaceuticals and pesticides in various matrices.

키워드

Deep eutectic solvents; Green analytical chemistry; Sample pretreatment; Pharmaceuticals; Pesticides

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