Extracorporeal Circulation Combined with Hypothermia and Hemodilution Technique
Hong Pil-Whoon, Lee Sae-Soon, Hong Sung-Nok, Kim Sae-Whan,
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( Hong Pil-Whoon ) - ¿¬¼¼´ëÇб³ Àǰú´ëÇÐ ¿Ü°úÇб³½Ç
( Lee Sae-Soon ) - ¿¬¼¼´ëÇб³ Àǰú´ëÇÐ ¿Ü°úÇб³½Ç
( Hong Sung-Nok ) - ¿¬¼¼´ëÇб³ Àǰú´ëÇÐ ¿Ü°úÇб³½Ç
( Kim Sae-Whan ) - ¿¬¼¼´ëÇб³ Àǰú´ëÇÐ ¿Ü°úÇб³½Ç
KMID : 0311119630040010058
Abstract
A hypothermic, low flow perfusion, using 5% dextrose in water as the priming fluid in the pump-oxygenator, was carried out to observe oxygen consumption, blood pH changes, and CO2 tension during the bypass period.
A low oxygen consumption which was approximately one third of the preperfusion value, was observed during the total by-pass period. This is believed to be due to the effect of low flow rates employed, hypothermia and low CO2 tension observed in these animals.
The pH of the arterial blood and the partition of the total CO2 remained within a fairly normal range. There was a marked reduction in CO2 tension during the bypass period. Its harmful effect on the oxyhemoglobin dissociation curve and cerebral circulation was discussed.
The hemodilution attendant to the use of 5% dextrose in water as the priming fluid is considered insignificant.
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