A Phase-Contrast Microscopic Study on the Induction of Cellular Deformation in Mast Cells
Choi Kum-Duck, 오영근, Park Dal-Uck, Rhim Kyu-Soon, Cho Tong-Hun,
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( Choi Kum-Duck ) - 연세대학교 의과대학 해부학교실
오영근 ( Oh Yung-Keun ) - 연세대학교 의과대학 해부학교실
( Park Dal-Uck ) - 연세대학교 의과대학 해부학교실
( Rhim Kyu-Soon ) - 연세대학교 의과대학 해부학교실
( Cho Tong-Hun ) - 연세대학교 의과대학 해부학교실
KMID : 0311119660070010001
Abstract
The influence of colchicine, colcemid, ginseng-alcohol extract, saponin, garlic alcohol-ether extract, and X-irradiation on free floating peritoneal mast cells were studied in rats by means of a phase contrast microscope. After the intraperitoneal injection of colchicine or colcemid the mast cells of the albino rat peritoneal fluid show an altered morphology. Ginseng-alcohol extract, allicin extracted from garlic, and X-irradiation do not elicit this cytological response. Mast cells exposed to saponin exhibit a severe destruction and degranulation.
The relation of the mast cell-damaging agents, metabolic poisons, and X-irradiation to the mast cell response is discussed with reference to the morphological changes. These are compared with the data of Padawer (1960, 1966).
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