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A Study of High Mutability Involving Two Loci in Drosophila Melanogaster

Yonsei Medical Journal 1968³â 9±Ç 2È£ p.155 ~ 162
Yoon Jong-Sik,
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 ( Yoon Jong-Sik ) - Yonsei University College of Medicine Department of Physiology

Abstract


Data are presented which strongly indicate that the locus occupied by the mutant ws lies to the left of, or on the same locus of apricot (w^(¥á)). The fact that w shows a non-suppressor effect in combination with zeste as a typical phenomenon in mutants of sites 1, 2, and 3 of the white locus, also supports that W is a mutant at or left of apricot (site 3). A "model" for the genetic fine structure of the mutants (w^(2m), w^(zl), and w^(z)) is proposed and discussed to account for the mutability among those three mutants. Analysis of ws leads to the hypo-thesis that it is the result of an inversion (sites 3 and 4) at the white locus, by two mechanisms which are discussed briefly here.

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