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Adenoacanthoma of Pyloric Antrum of the Stomach

Yonsei Medical Journal 1970년 11권 1호 p.60 ~ 66
이유복, 최인준,
소속 상세정보
이유복 ( Lee Yoo-Bock ) - Yonsei University College of Medicine Department of Pathology
최인준 ( Choi In-Joon ) - Yonsei University College of Medicine Department of Pathology

Abstract


In view of rarity and its unsolved histogenesis, a case of adenoacanthoma at the pyloric antrum of the stomach is reported.
The patient was a 43 years old Korean male teacher who had onset of symptoms referable to present illness three months prior to the admission, although he had ulcer symptoms 7 years previously and subsequently free from the symptoms during last 4 years following 3 years´ anti-ulcer regimen.
Histopathologic studies of the stomach revealed a large ulcerated lesion at the pyloric antrum, and it was predominantly a well differentiated squamous cell carcinoma occupying the central and superficial part and surrounded by a narrow rim of adenocarcinoma at the periphery. Multiple regional nodes examinations disclosed metastases of only adenocarcinoma in 5 nodes and no metastasis of squamous element was found.
A brief review of the literature and a discussion concerning clinical, histopathologic and especially histogenetic aspects is made. It was interesting to note that all squamous cell nests are surrounded by multi-layers of small indifferent basal type of cells, and it was thought that this might possibly be a supportive evidence ofdirect stimulation to basal cells to differentiate into squamous element.

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