Hematological Aspects of Congenital Syphilis
Kim Kir-Young, ±è¼öÇü,
¼Ò¼Ó »ó¼¼Á¤º¸
( Kim Kir-Young ) - Yonsei University College of Medicine Department of Pediatrics
±è¼öÇü ( Kim Soo-Hyung ) - Yonsei University College of Medicine Department of Pediatrics
KMID : 0311119760170020142
Abstract
Hematologic investigations for 7 years at the Pediatric Department of Yonsei Medical Center of 52 syphilitic infants were reviewed. A moderate degree of anemia with red cell regeneration was observed in 40 infants (76.0 %). Marked thrombocytopenia but without active bleeding was found in 19 infants, and with active bleeding in 3 infants. A wide range of leukocyte counts, relative lymphocytosis and monocytosis were prominant features. The jaundice was mainly due to unconjugated bilirubin in 6 infants, conjugated as well as unconjugated bilirubin in 8 infants. With therapy, the above abnormal hematologic findings showed marked improvement. Early diagnosis is essential. Prevention and congenital syphilis depend on a high level of clinical suspicion, supported by routine and diagnostic use of laboratory and serologic aids, in the asymptomatic or minimally symptomtaic infants.
Ű¿öµå
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸