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免疫學的 生着增强作用

Immunological enhancement

감염 1972년 4권 1호 p.21 ~ 47
이종훈,
소속 상세정보
이종훈 (  ) - 가톨릭의과대학 미생물학교실

Abstract


1) In 1951^-1953, the incidence of Epidemic Hemorrhagic Fever was high in those united nation´s allied forces residing in the front line of korean conf lict. However, the incidence of the Hemorrhagic Fever was declined in the personneles of the allied forces since the armistice July 1953, and it has been gradually increased in korean army and the Hemorrhagic Fever becomes one of the military diseases of major concerns in Korea.
Incidences of Hemorrhagic Fever have been reported even in the civilians living in the southern part far below the front-line since 1965.
In 1971, the epidemic incidence of Hemorrhagic Fever in almost every area of south Korea has been reported in civilians and the incidence exceeded that of military personnels, which has brought about sociomedical concerns (Table 1, Fig. 1).
2) The incidence of Hemorrhagic Fever has been reported year around, although there seems to have two peaks in the incidence curve, namely late spring (may to june) and late fall (october to december). In the military personnel residing in highly infectious area, the main peak were reported to be located in the second peak of "the late fall". However, analysis on the incidence of the civilian group residing in less highly infectious area shows that there is only one peak (late fall) in the incidence curve which simulates the incidence curve observed in northern Manchuria and asian Russia.
3) It has been accepted that there is no sexual, age or racial difference in the susceptability of the disease.
In those neighbouring areas of the front line (of cease-fire) considered to be highly infectious area, mainly consisting of farmers working vigorously together without sexual difference, the incidence of the disease was same among male and female. Hewever, in those areas far from the front line, less highly infectious area, the male to female ratio of the incidence was 2, 6-4, 2 : 1.
The increased incidence in male was ascribed to the fact that the males had more chance to be exposed to the infectious agent from the view point of environmental ecology. It is analogous to the decreased incidence in patients of younger and older age group in whom physical activity is relatively limited and chances to be exposed to the infectious agent seem to be less (Table 6, 7).
4) 70 to 80% of infected patients consisted of the age group in their vigorous activity ranging 20 to 50 year old age group. This was also ascribed to the increased chance of exposure to the infec-
don. Fatality rate was also higher in this group of patients engaged in vigrous physical activity,than those in younger or older age group.

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