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高 및 低蛋白食으로 飼育한 白鼠에 있어서 血中放射能標識 Amini酸의 各組織蛋白合成에 編入되는 速度에 關하여

Comparisons of Incorporation Ratesof Intravenously Injected Amino Acid Mixed-C11 into Various Tissues of Rat Fed on High and Low Protein Diets

경북의대잡지 1967년 8권 2호 p.313 ~ 319
김상직,
소속 상세정보
김상직 (  ) - 경북대학교 의과대학 생화학교실

Abstract


Comparisens wee made on incorporation of intravenously injected amino acid nixed-C1 ( AI7a1 ?rot^in IZ;~drolysate-C´ ~~ in plasma and tissue prot is between high{ and low protein diet raats.
1) Prelminary erirent reveand ti?at 15 :.ou;s of astin; a~ ter the adn:inistraticn of amino acid mixed .L seemed to be adequate to observe the laxir.ut incorporation cf the amino acid in plaslra ulld liver proteins and the minimum activity of nonprotein-C1 inplasma.
2) The incorporation of amino acid mired-C1 in tissue protein, at the 15th hour of fasting, was remarkably higher in liver, kidney, spleen, adren~,a, and .intestine on ´loth high and lew protein c:ie,, ats.
3) A compaltion of the incorporated C^14 activity in tissue pxetein of both rats revealed a higher tissue protein C´-4 activity in most tissues of low protein diet rats; especially in the liver, it was 2 times as high.
4) Total non-protein-C14 activity excreted in urine for 15 hours showed no significant difference between both rats: in high protein diet rat 6.80.78 % of the injected; and in losvprotein diet rat 5.70.87%.
5) Amino acid nitrogen concentration in each tissur, showed no significant difference between both diets rats.

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