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生長期 鷄肝의 Phosphoenolpyruvate Carboxykihase의 變動에 관하여

Study of Developmental Changes of Phosphoenolpyruvate Carboxykinase in Developing Chichen Liver

경북의대잡지 1976년 17권 1호 p.88 ~ 92
조윤애, 曺準承,
소속 상세정보
조윤애 (  ) - 慶北大學校 醫科大學 生化學敎室
曺準承 (  ) - 慶北大學校 醫科大學 生化學敎室

Abstract


This study is undertaken to investigate the change of phosphoenolpyruvate carboxykinase (EC 4. 1.1.32) activity during the chicken liver development. The results obtained were summerized as follows;
1. During one week before and following the hatching, the chicken liver showed a rapid growth in size and a linear increase in weight: the liver weigi!~t was O. lg on the 14th day embryo, 0, gg immediately after hatching and 1.4 on the 7th days.
2. From early embryonic stage the enzyme was determined in both fractions of miotchondria and cytoplasm of the liver. However, the enzyme activity was high in the mitochondria but very low in the cytoplasm, with changes as the embryo chick grew.
3. The rise in the activity of the enzyme of the embryo chick liver reached the peak within 2 to 3 days following the hatching to decline to the levels of an adult Iiver by the 15th day after the hatching. The pattern of the developmental increase iri the activity of cytoplasmic enzyme was sharper thau that of the mitochondria.

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