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급성일산화탄소 중독이 뇌파에 미치는 영향

Effects of Acute Carbon Monoxide Poisoning on the Electroencephalogram of the Rabbit

경북의대잡지 1978년 19권 1호 p.21 ~ 29
김재식, 김미한, 박정희, 문정숙,
소속 상세정보
김재식 (  ) - 경북대학교 의과대학 생리학교실
김미한 ( Kim Mi-Han ) - 경북대학교 의과대학 마취과학교실
박정희 (  ) - 경북대학교 의과대학 생리학교실
문정숙 (  ) - 경북대학교 의과대학 생리학교실

Abstract


In order to observe the effects of the acute carbon monoxide poisoning on experimental animals, rabbits were exposed to the 0.2 %and 0.5% carbon monoxide gas mixtures with room air. The duration of the exposure in the 0.2% concentration was 100 minutes and that in the 0.5% concentration was 30 minutes.
The EEG was recorded with the fronto-occipital bipolar lead.
The stainless steel needle electrodes were implanted extradurally through skull bone.
The EEG of rabbits in the acute carbon monoxide poisoning showed a generalized diminished voltage in the amplitude and a slightly decsea&ed frequency in file rhythm of the main waves. During the recovery period the relatively high voltage sl~~~v wave activity were observed on several occasions. The above EEG abnormalities were similar to tl:~e previously reported EEG findings in the rabbits exposed to the positive(=Gz) and negative acceleratron(Gz), and the rapid decompression.
There are individual variations in the length of the recovery period from the acute carbon monoxide poisoning at the same concentration of the gas mixture.
The individual variation of the recovery period of the EEG seems to be originated by the tolerance of each animal to the carbon monoxide poisoning and also the tolerance to the gas poisoning will largely depend upon the degree of the resultant brain hypoxia.

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