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眞菌類에 對한 各種藥劑의 抗菌效果

Actions of Antifungal Compounds and Drugs against Pathogenic Fungi

경북의대잡지 1978년 19권 2호 p.110 ~ 114
김상윤, 鄭在奎,
소속 상세정보
김상윤 (  ) - 慶北大學校 醫科大學 細菌學敎室
鄭在奎 (  ) - 慶北大學校 醫科大學 細菌學敎室

Abstract


Difolatan, an agricultural fungicidal compound, was studied to know the antifungal effects of both growth inhibitory and fungicidal actions against Candida sp., Aspergillus sp. and Trichlophyton sp., and these actions were compared with the currently available therapeutic drugs.
Against Candida sp. difolatan showed a strong antifungal action as phenyl mecrcuric acetate did and was stronger than the action of gentian violet. However, griseofulvin, miconazole and tolnaftol exhibited no such effects at all.
Growth of Aspergillus sp. was strongly inhibited only by difolatan phenyl mercuric acetate, and Tricophyton sp. was suppressed strongly by difolatan, phenyl mercuric acetate and tolnaftol, but weakly by griseofulvin.
Fungicidal actions of difolatan as well as phenyl mercuric acetate were stronger against Trichophyton sp. than Aspergillus sp.

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