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소아 뇌종양의 임상 및 방사선 소견에 대한 고찰

Clinical and Radiologic Observations on Brain Tumors in children

계명의대논문집 1993년 12권 4호 p.544 ~ 554
강진무, 조성범, 김흥식, 김명성,
소속 상세정보
강진무 (  ) - 계명대학교 의과대학 소아과학교실
조성범 (  ) - 계명대학교 의과대학 소아과학
김흥식 (  ) - 계명대학교 의과대학 소아과학교실
김명성 (  ) - 계명대학교 의과대학 소아과학교실

Abstract


The analysis of the clinical and radiological findings were performed on 41 cases of brain tumor in children under the age of 15 years who were admitted to Pediatric department of Dongsan Medical Center, Keimyung University, School of Medicine
between
May 1987 and September 1992. The clinical and radiological findings were analysed retrospectively.
@ES The results were as follows:
@EN The male to female ratio was 2.7 : 1 and the peak incidence of age was between 10 and 15 years(39.0%).
The supratentorial tumors were found more frequently(60.9%) than the infratentorial tumors(39.1%).
Histopathologically, the astrocytoma was most common(24.4%), followed by medulloblastoma, ependymoma, craniopharyngioma.
The main symptoms of the supratentorial tumors were headache(64.0%), vomiting(56.0%), nausea(44.0%), visual disturbance(32.0%), convulsion(24.0%), and endocrine dysfunction(8.0%), in order of frequency.
Those of the infratentorial tumors were vomiting(87.5%), nausea(75.0%), headache(62.5%), papilledema(37.5%), ataxia(25.0%), convulsion(18.8%).
The brain CT findings were different according to the histopathological findings. Most of the astrocytoma showed cystic nature, low density, and inhomogenous enhancement. Medulloblastoma was mostly located at infratentorium, and showed well
enhancement
and hydrocephalus in all cases. Craniopharyngioma showed suprasella hypodensed mass lesions with calcificaion in all cases. Ependymoma showed well enhancement and marked hydrocephalus in all cases.
40 cases except one case of metastatic ganglioneuroblastoma had undergone complete or partial resection. Twelve patients were irradiated and 3 patients received chemotherapy after surgery. Eight patients received combined therapy with surgery,
radiotherapy and chemotherapy.
Out of 40 cases who received surgery, the follow up study was possible on 24 cases of which 11 cases have been alive, including 5 cases who has been survive more than 2 years.

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