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Combined modality therapy in stage I. II head and neck non-Hodgkin's Lymphoma

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Abstract


Between 1983 and 1992, 18 patients with stage I, II intermediate grade head and neck non Hodgkin's lymphoma were treated with a combination chemotherapy and involved field radiotherapy. Mean age was 50.3 years and 7 patients were 60 years old.
12(66.7%)
achieved a complete response(CR) and 5(27.8%) had a partial response after chemotherapy, and additional 5 patients achieved a CR after radiotherapy. The 8-year total survival rate was 82.4% and 8-year relapse free survival of CRs was 87.5% with a
median
follow-up of 48.9 months. The age, sex, stage, histology and extranodal involvement did not influence the outcome. Also total survival time was not related to age, performance score and various laboratory parameters.

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