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비파열성 난관임신에 대한 Methotrexate의 보존적 치료효과

Conservative treatment of unruptured tubal pregnancy with methotrexate

계명의대논문집 1994년 13권 1호 p.107 ~ 110
홍원표, 박기락,
소속 상세정보
홍원표 (  ) - 계명대학교
박기락 (  ) - 계명대학교

Abstract


Four subjects with unruptured tubal pregnancies were treated with four doses of intramuscular methotrexate (1.0mg/kg) followed by four doses of citrovorin factor (0.1mg/kg). The diagnosis was established in all cases by sonography and
radioimmunoassay
for serum β-subunit of human chorionic gonadotropin.
Subjects were followed with quantitative serum β-human chorionic gonadotropin radiommunoassay and sonography. Three of the four subjects experienced resolution of their ectopic pregnancy without additional surgical treatment. One subject
underwent
salpingectomy due to failure of medical treatment.
Further comparative studies and long-term follow-up are needed to evaluated reproductive outcome but the use of methotrexate seems to be valuable in the treatment of some selected cases of tubal pregnancy.

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