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Leiomyosarcoma of the jaw: case series

대한구강악안면외과학회지 2020년 46권 4호 p.275 ~ 281
최용석, Almansoori Akram Abdo, 정태영, 이재일, 김성민, 이종호,
소속 상세정보
최용석 ( Choi Yong-Suk ) - Seoul National University Dental Hospital Department of Oral and Maxillofacial Surgery
 ( Almansoori Akram Abdo ) - Seoul National University Dental Hospital Department of Oral and Maxillofacial Surgery
정태영 ( Jung Tae-Young ) - Seoul National University Dental Hospital Clinical Translational Research Center for Dental Science
이재일 ( Lee Jae-Il ) - Seoul National University Dental Hospital Department of Oral Pathology
김성민 ( Kim Soung-Min ) - Seoul National University Dental Hospital Department of Oral and Maxillofacial Surgery
이종호 ( Lee Jong-Ho ) - Seoul National University Dental Hospital Department of Oral and Maxillofacial Surgery

Abstract


Objectives: Leiomyosarcoma is a malignant neoplasm that affects smooth muscle tissue and it is very rare in the field of oral and maxillofcial surgery. The purpose of this study was to obtain information on diagnosis of and treatment methods for leiomyosarcoma by retrospectively reviewing of the cases.

Patients and Methods: The study included nine patients who were diagnosed with leiomyosarcoma in the Department of Oral and Maxillofacial Surgery at Seoul National University Dental Hospital. The subjects were analyzed with respect to sex, age, clinical features, primary site of disease, treatment method, recurrence, and metastasis.

Results: Particular clinical features included pain, edema, mouth-opening limitations, dysesthesia, and enlarged lymph nodes. All cases except one were surgically treated, and recurrence was found in two cases. Four of nine patients were followed up without recurrence and one patient underwent additional surgery due to recurrence.

Conclusion: In our case series, notable symptoms included pain, edema, mouth-opening limitations, and dysesthesia; however, it was difficult to label these as specific symptoms of leiomyosarcoma. Considering the aggressive characteristics of the disease and poor prognosis, surgical treatment is necessary with careful consideration of postoperative radiotherapy and chemotherapy.

키워드

Leiomyosarcoma; Mouth neoplasm; Case series

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