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신결석 및 뇨관결석 환자 수술시 Mannitol 투여 예

Mannitolization during Operation of Patients with Urinary Stone

대한마취과학회지 1977년 10권 2호 p.113 ~ 117
김난숙, 이경자, 길찬일, 신정순,
소속 상세정보
김난숙 (  ) - 고려대학교 의과대학 마취과학교실
이경자 (  ) - 고려대학교 의과대학 마취과학교실
길찬일 (  ) - 고려대학교 의과대학 마취과학교실
신정순 (  ) - 고려대학교 의과대학 마취과학교실

Abstract


It is well known that general anesthesia and surgery cause acute depression of renal function.
Also, the occurrence of frank bleeding from the urinary tract can form a blood clot which may block an indwelling catheter or even a normal urethra with development of urinary infection.
Many studies have reported that prophylactic use of hypertonic mannitol will prevent acute functional renal impairement during general anesthesia and surgery, and reduce the incidence of clot formation and acute pyelonephritis.
We believe that diuresis itself is a renoprotective mechanism and polyuria may yield two other advantages:
1. Fewer plugged catheters by decreasing the incidence of clots.
2. Decreased incidence of acute pyelonephritis by preventing stasis and washing out bacteria.
since 1972, in our hospital, 100 ㏄ or 200 ㏄ of 20% mannitol was used for increasing the urine output during operation of urinary stone in 33 patients,
We have shown that the prognosis of patients was good.

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