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The Clinical Usefulness Evaluation of Normal Saline Injection in Coronary Artery Computed Tomography Angiography(Coronary CTA)

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Á¤°­±³, À̹ÌÈ­, Á¶Æò°ï,
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Á¤°­±³ ( Jung Kang-Kyo ) - ´ë±¸°¡Å縯´ëÇб³ ¹æ»ç¼±Çаú
À̹ÌÈ­ ( Lee Mi-Hwa ) - ´ë±¸°¡Å縯´ëÇб³ ¹æ»ç¼±Çаú
Á¶Æò°ï ( Cho Pyong-Kon ) - ´ë±¸°¡Å縯´ëÇб³ ¹æ»ç¼±Çаú

Abstract

º» ¿¬±¸´Â bolus tracking methodÀ» ÀÌ¿ëÇÑ °ü»óµ¿¸ÆÀü»êÈ­´ÜÃþÁ¶¿µ°Ë»ç(coronary artery CT angiography,ÀÌÇÏ coronary CTA)¿¡¼­ Á¶¿µÁ¦ ÁÖÀÔ Àü »ý¸®½Ä¿°¼ö(normal saline) Åõ¿©¸¦ ÅëÇØ º¯È­µÇ´Â ½É¹Úµ¿¼ö(heart rate) Ư¼ºÀ» °í·ÁÇÑ ÃÔ¿µ¹æ¹ý º¯È¯À¸·Î ¿µ»óÀÇ Áú°ú ¼±·®¿¡ ¹ÌÄ¡´Â °ü°è¸¦ º¸°íÀÚ ÇÏ¿´´Ù. ¿¬±¸´ë»óÀÚ´Â °Ç°­°ËÁøÀ» ¸ñÀûÀ¸·Î °Ç°­°ËÁø¼¾ÅÍ¿¡ ³»¿øÇÏ¿© coronary CTAÀ» ½ÃÇàÇÑ 200¸íÀÇ »ç¶÷À» ´ë»óÀ¸·Î Æò°¡ÇÏ¿´´Ù. ±× °á°ú ¼±·®Æò°¡¿¡¼­´Â ÀüÇâÀû µ¿Á¶È­°¡ ÈÄÇâÀû µ¿Á¶È­º¸´Ù À¯È¿¼±·®ÀÌ 6.0¡¾1.0 mSv(54.1%) °¨¼ÒµÇ¾ú´Ù. Æò±Õ ½É¹Úµ¿¼ö´Â ½ÉÀåÇ÷°üÈ®ÀåÁ¦ ´ÏÆ®·Î±Û¸®¼¼¸°(nitroglycerin, ÀÌÇÏ NTG) ¼·Ãë ÈÄ º¯È­µÈ Æò±Õ ½É¹Úµ¿¼ö¿Í »ý¸®½Ä¿°¼ö Åõ¿© ÈÄ º¯È­µÈ Æò±Õ ½É¹Úµ¿¼ö ºñ±³¿¡¼­ 4.8¡¾0.3 bpmÀÇ À¯ÀÇÇÑ Â÷ÀÌÀÇ °¨¼Ò¸¦ º¸¿´°í ½É¹Úµ¿¼ö º¯È­ÀÇ Æø(heart rate area)¿¡¼­´Â Æò±Õ 4.7¡¾2.0 bpmÀÇ °¨¼Ò¸¦ º¸¿´´Ù. ¿µ»óÆò°¡¿¡¼­´Â SNR°ú CNR, ±×¸®°í blurring Á¤µµÀÇ Æò°¡¿¡¼­ ¸ðµÎ ½É¹Úµ¿¼ö°¡ °¨¼ÒµÊ¿¡ µû¶ó À¯ÀÇÇÑ Â÷À̸¦ º¸¿´´Ù. ÀÓ»ó¿¡¼­ coronary CTA¿¡¼­ ÇÇÆø¼±·® °¨¼Ò¿Í ¿µ»óÀÇ Áú Çâ»óÀ» À§ÇØ Á¶¿µÁ¦ ÁÖÀÔ Àü¿¡ »ý¸®½Ä¿°¼ö Åõ¿©¸¦ ÅëÇÑ ½É¹Úµ¿¼ö Ư¼º°üÂûÀÌ ¿ä±¸µÈ´Ù.

The purpose of this study is that in coronary artery angiography computed tomography (coronary CTA), to gain high quality of image and to use low dose radiation by administrating normal saline and converting the mode of scanning heart rate (HR) characteristics before infusing contrast media. All patients data (total specimens: 200, male: 108, female: 92) were measured by using appropriate mode of scanning the heart rate (HR) after injection of saline. in addition we measured radiation dose (CTDIvol, effective dose) in all examinations. CT number and noise, and blurring of coronary artery (proximal RCA, middle RCA, proximal LCA) were measured and compared. The result of this study after injection of saline, mean heart rate was decreased about 4.8¡¾0.3 bpm (beats per minute). 33 patients (13%) got converting scan mode due to reducing heart rate (HR). In prospective gating mode, radiation dose were measured less 6.0¡¾1.0 mSv (54.1%) than retrospective gating mode. Also showed a significant difference in heart rate decrease in image evaluation.

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½É¹Úµ¿¼ö; »ý¸®½Ä¿°¼ö; ÀüÇâÀû µ¿Á¶È­; ÈÄÇâÀû µ¿Á¶È­
Coronary CTA; Heart rate; Normal saline; Contrast media; Scan mode

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