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Ethionine 투여로 인한 정상상피세포의 선체변화

The Changes of Acrosome of Rat Germinal Epithelium Induced by Ethionine Feeding

대한병리학회지 1977년 11권 4호 p.315 ~ 320
김시오, 홍정길, 황선호,
소속 상세정보
김시오 (  ) - 경북대학교 의과대학 병리학교실
홍정길 (  ) - 경북대학교 의과대학 병리학교실
황선호 (  ) - 경북대학교 의과대학 병리학교실

Abstract


The author studies the effect of ethionine upon the acrosome formation of spermatozoa
in albino rats.
Five tenth percent of DL-ethionine was added to the diet of the experimental group
rats and they were sacrificed after l,2,3, and 4 weeks, respectively. The testes were
observed by electron microscope:
The results obtained were summurized as follow:
The changes were decrease in electron density and irregularity of margin in acro-
somes, vacuolization, irregularity of margin and increase or decrease in electron density
in head cap, poorly defined border between acrosome and head cap, and decrease of
Golgi remnant. These changes were occurred at second to third weeks from start of
ethionine feeding and more severe at fourth week.
These overvation suggested ethionine induced degenerative changes of acrosome and
its related structures, characterized by decrease of electron density, vaculization and
irregularity of their margin. The degenerative changes of these structure were consi-
dered to be induced by secondary effects of damage to other organelle, such as mito-
chondria and so.

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