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자궁 경부암 조직과 만성 자궁 경부염조직의 산성점액질에 관한 조직화학적 연구

A Histochemical Study on Acid Mucopolysaccharide of the Uterine Cervix with Carcinoma and Chronic Inflammation

대한병리학회지 1978년 12권 2호 p.159 ~ 170
손한철, 김순호,
소속 상세정보
손한철 (  ) - 부산대학교 의과대학 임상병리학교실
김순호 (  ) - 부산대학교 의과대학 임상병리학교실

Abstract


In an attempt to elucidate the state of acid mucopolysaccharide of uterine cervix with
carcinoma and chronic inflammation, the author examined histochemically 27 cases of the
squamous cell carcinoma and 62 cases of chronic cervicitis with erosion, squamous
metaplasia or dysplasia. These were obtained by total hysterectomy and biopsy in Busan
National University Hospital during the period of 1975 and 1976.
By the examination the following results were obtained :
1. In the mucosa of the chronic cervicitis the surface epithelium did not containe acid
mucopolysaccharide.
2. In the mucosa of the chronic cervicitis the metaplastic and dysplastic squamous
epithelium contained very small to small amount of acid mucopolysaccharide, but the
malignant squamous cells did not contain acid mucopolysaccharide.
3. The surface columnar epithelium in the mucosa of the chronic cervicitis contained
more large amount of the acid mucopolysaccharide than that of the non-cancerous tissue
of the cervical carcinoma.
4. The acid mucopolysaccharide of the glandular epithelium was not significantly
different in amount between the mucosa of the chronic cervicitis and the non-cancerous
tissue of the cervical carcinoma.
On the basis of mentioned above, it may be somewhat helpful to examine the state of
acid mucopolysaccharide of the cervical mucosal epithelium in differentiation between the
cervical carcinoma and chronic cervicitis with metaplasia or dysplasia.

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