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한국인의 SMA 12/60 분석치 판독을 위한 컴퓨터의 이용에 관한 연구

A Computer Diagnostic System Based on Automated Multiphasic Screening by SMA 12/60 on Korean

대한병리학회지 1978년 12권 4호 p.407 ~ 412
권오헌, 이귀녕, 김선구,
소속 상세정보
권오헌 (  ) - 연세대학교 의과대학 임상병리과
이귀녕 (  ) - 연세대학교 의과대학 임상병리과
김선구 (  ) - 연세대학교 의과대학 임상병리과

Abstract


Since the report of Bayes' theorem in 1763, many studies have been made to set
various discase patterns using a mathematical probability. However, most of those were
too convenient for practical use. Fortunately the recent development of computer system
solved some of these problems. Reece and Hobbie(1971) developped the System of
Organizing Relevant Tests(SORT). SORT is a kind of approach to find out the most
probable disease pattern, delived from 12 different biochemical data of SMA 12/60
interpreted in regard to the sex and age.
This study is conducted to apply the SORT on Korean. First, the Korean normal
values in regard to the sex & age were calculated by Hoffmann's method. Then a
random selection of 100 patients with various discharge diagnosis were selected. On
these patients, the SORT was applied.
1. The normal values was obtained by the Hoffmann's method.
2. The normal values of 12 biochemical tests reveal the following characteristics, in
general compared with those of the white population.
ⅰ) Calcium, phosphorus, BUN, uric acid and cholesterol are relatively low.
ii) Alkaline phosphatase and LDH tend to be high.
iii) Total protein, albumein and bilirubin are almost the same.
iv) SGOT is almost same in upper limit and low in lower limit.
3. When only 5 possible disease entities were taken in consideration, the SORT was in
consistent with the discharge diagnosis in a rate of 24%, If 10 were taken, the
consistency rate becomes 47%.
4. It was discussed that the consistency rate will be raised if the inherited
disadvantages of Hoffmann's method were supplemented and if the sample sizes were
expanded.
5. The SORT expences per patient were about 20 Won, after the computer
Programming was completed. It was considered Quite inexpensive for a practical use.
6. The routine application of SORT was considered to be beneficial for both the patient
and doctor to make an early diagnosis otherwise might be overlooked.

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