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역간접 적혈구 응집반응에 의한 혈청 HBsAg와 간접 적혈구 응집반응에 의한 혈청 anti-HBsAg의 검출

Detection of Serum HBsAg by Reserved Passive Hemoagglutination and Serum Anti-HBsAg by Passive Hemoagglutination

대한병리학회지 1979년 13권 1호 p.29 ~ 38
이은엽, 박복희, 왕수건,
소속 상세정보
이은엽 (  ) - 부산대학교 의과대학 임상병리학교실
박복희 (  ) - 부산대학교 의과대학 임상병리학교실
왕수건 (  ) - 부산대학교 의과대학 임상병리학교실

Abstract


The authors investigated serum HBsAg and anti-HBsAg by methods of
counterimmunoelectrophoresis(CIEP) and reverses passive hemagglutination(r-PHA) and
passive hemagglutination(PHA)
The sera were obtained from 1502 cases of healthy control, 530 cases of acute liver
damage and 480 cases of chronic liver damage in Busan National University Hospital
during the year of 1977. We compared serum HBsAg and anti-HBsAg positive rates
between two methods and the following results were obtained.
1. In the healthy control, acute and chronic liver damage, serum HBsAg positive rates
4.5, 17.1 and 22.9% by R-PHA were significantly higher than those 2.3, 5.3 and 9.2% by
CIEP, respectively.
2. In the healthy control, acute and chronic liver damage, serum anti-HBsAg positive
rates 13.8, 14.9 and 17.5% by PHA were significantly higher than those 0.3, 0.4 and
1.5% by CIEP, respectively.
On the basis of above mentioned results, R-PHA and PHA tests proved to be more
sensitive than CIEP in detection of serum HBsAg and anti-HBsAg.

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