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정상임부에 있어서의 혈청 CAP와 LAP 활성도

The Serum CAP and LAP Activities in Normal Pregnant Women.

대한병리학회지 1979년 13권 2호 p.95 ~ 102
주수자, 오선옥, 조명준,
소속 상세정보
주수자 (  ) - 국립의료원 임상생화학과
오선옥 (  ) - 국립의료원 임상생화학과
조명준 (  ) - 국립의료원 임상생화학과

Abstract


The values of the serum cystine aminopeptidase and leucine aminopeptidase activities
in clinically healthy pregnant women have been studied using Iatron Kit according to
months of gestation periods.
1. The serum cystine aminopeptidase and leucine aminopeptidase activities in
extensively normal women (control group) were 13.75±2.67 munit/ml. and 170.33±33.39
G-R unit/ml. respectively, and fail to show remarkable changes in early pregnancy (up
to 5 months of periods).
2. The mean CAP and LAP activities in normal pregnant women showed progressive-
ly increasing tendency by months of gestation with a mean of 175±64.30 munit/ml. and
517.2±165.47 G-R unit/ml. at term. About 15 fold increased value in CAP and 3 to 4
fold increased value in LAP than those of early pregnancy and control group were noted
at term.
3. A positive correlation (P<0,005) was found between cystine aminopeptidase and
leucine aminopeptidase activities in pregnant women.
It is, therefore, suggested that the comparative evaluation of cystine aminopeptidase
and leucine aminopeptidase activities, relatively simple and easy to perform, could be
used as a parameter in judging the functional state of the placenta during late
pregnancy.

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