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정상임신부 및 자간전증 환자에서 출생시 태아체중에 따른 혈소판 및 혈청의 화학적 검사에 관한 연구

Study on the Platelet Counts and Blood Chemical Tests in Cases with Normal Pregnancy and Preeclampsia According to Birth Weight-for-Date Percentiles

대한산부인과학회지 1993년 36권 8호 p.3288 ~ 3296
안정자,
소속 상세정보
안정자 (  ) - 이화여자대학교

Abstract


This study was undertaken to evaluate if differences would be found in platelet counts and blood chemical assays between 4 (0~24.9, 25.0~49.9, 50.0~74.9, 75.0~100)birth preeclampsia and also between normal pregnant cases and preeclamptic cases in
the
same brith weight-for date percentile grup. 94 cases with mild preeclampsia, 82 cases with severe preeclampsia and 104 cases with normal pregnancy for control were taken part in this study at the Department of Obstetrics and Gynecology, Ewha
Woamns
University Hospital form January, 1989 to September, 1992.
Platelet counts, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total protein, albumin, blood urea nitrogen(BUN), and creatinine levels in cases with normal pregnancy, mild and severe preeclampsia according to birth
weight-for-date
percentiles were measured and analyzed.
@ES The result were as follows:
@EN 1. There were no significant differences on platelet counts between each birth weight for-date percentile groups in cases with normal pregnancy , mild and severe preeclampsia, and also between mild preeclamptic cases and normal pregnant cases
in the
same birth weight-for-date percentile group.
There were no significnat differences on platelet counts between severe preeclamptic cases and normal pregnant cases in the same birth weight-for-date percentile group except for 25.0~49.9 birth weight-for-date percentile group.
2. Serum Alt, AST, Total protein and albumin levels according to birth weight-for-date percentiles were not sighificnatly different in cases with normal pregnancy, mild and severe preeclampsia, respectively.
ALT levels in both of mild and severe preeclamptic cases were significantly higher than those of normal pregnant cases in all 4 brith weight-for-date percentile groups. Serum AST levels in severe preeclamptic cases of 0~24.9 birth weight-for date
percentile group were significantly higher than those in both of cases with normal pregnancy and mild preeclampsia of the same percentile group.
Serum total protein and albumin levels in severe preeclamptic cases of 0~24.9 percentile group were significatly lower than those in both of cases with normal pregnancy and mild preeclampsia of the same percentile group.
3. BUN levels in 50.0~74.9 percentile group were significantly higher than those in 25.0~49.9 percentile group of normal pregnant cases and those in 50.0~74.9 percentile group were significantly lower than those in both of 0~24.9 and 25.0~49.9
percentile group in mild preeclamptic cases.
BUN levels were not sihificantly different between each percentile groups in severe preeclamptic cases
BUN levels in both of mild and severe preeclamptic cases were significantly higher than those of normal pregnant cases in all 4 percentile groups.
Serum creatinine levels according to birth weight-for-date percentiles were not significantly different in cases with nomal pregnancy, mild and severe preeclampsia. Serum creatinine levels in both of mild and severe preeclamptic cases were
significantly
higher than those of normal pregnant cases in all 4 percentile groups.

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