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체외수정 및 배아이식술에 있어서 착상예측에 대한 자궁내막 두계 측정의 효용성

The Effectiveness of Endometrial Thickness for Prediction of Implantation in IVF & ET

대한산부인과학회지 1993년 36권 12호 p.3912 ~ 3919
소속 상세정보
권혁찬 조동제/오기석/송찬호

Abstract


To determine whether preovulation endometrial thickness are related to fecundity in IVF-ET, endometrial thickness was evaluated by ultrasound on the day of hCG after FSH/hMG during 527 cycles of IVF-ET.
Eodometrial thickness was related to fecundity. For pregnant cycles, ninty-five percent of confidence bounds were 6.69 mm and 14.69mm. If a confidence bound of 6.69 mm was chosen for a low cut-off value of endometrial thickess, positive
predictive
value
was 89.3% (sensitivity 6.2%; specificity 97.6%) and for a confidence bound of 14.69mm as a high cutoff value, posisitive predictive value was 84.2%(sensitivity 4.0%; specificity 97.6%). No pregnancies occured when thickness was <5.9mm and >15mm.
The
highest fecundity was 27.8% between 10.7mm and 14.6mm inendometrial thickness, compared with 15.6% and 24.2% when thickness were 6.7mm to 8.6 mm and 8.7mm to 10.6mm. but there was no difference in clinical abortion rate and chemical pregnancy
rate
among
them. The ROC curve for endometrial thickness is flat and lies near diagonal, and logit coefficients for selected variales within the range of 2 SD revealed that the number of transferred embryos (P<0.05) and age of the patients(P<0.05) had
effect
on
fecundity, more strongly than the endometrial thickness(P<0.1). the result of logistic regression analysis with Dummy variables was that the cycle fecundity between 10.7mm and 14.6mm in endometrial thickness was significantly higher than the
fecundity
of 6.7mm to 8.6mm and 8.7mm to 10.6mm in endometrial thickness.
From this data we can conclude that endometrial thickness on the day of hCG admi

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