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Peptide YY producing strumal carcinoid tumor of the ovary in a postmenopausal woman: a rare cause of chronic constipation

대한산부인과학회지 2017년 60권 6호 p.602 ~ 607
Noh Hye-Kyung, 권병수, 김윤화, 이남경, 최경운, 서동수, 이동형, 김기형,
소속 상세정보
 ( Noh Hye-Kyung ) - Pusan National University School of Medicine Department of Obstetrics and Gynecology
권병수 ( Kwon Byung-Su ) - Pusan National University School of Medicine Department of Obstetrics and Gynecology
김윤화 ( Kim Yoon-Hwa ) - Pusan National University School of Medicine Department of Obstetrics and Gynecology
이남경 ( Lee Nam-Kyung ) - Pusan National University School of Medicine Department of Radiology
최경운 ( Choi Kyung-Un ) - Pusan National University School of Medicine Department of Pathology
서동수 ( Suh Dong-Soo ) - Pusan National University School of Medicine Department of Obstetrics and Gynecology
이동형 ( Lee Dong-Hyung ) - Pusan National University School of Medicine Department of Obstetrics and Gynecology
김기형 ( Kim Ki-Hyung ) - Pusan National University School of Medicine Department of Obstetrics and Gynecology

Abstract


Strumal carcinoid tumor of the ovary is a rare subtype of ovarian carcinoid tumors; it is characterized by an intimate mixture of thyroid and carcinoid tissues. We present a case of a 64-year-old woman who presented with the chief complaint of persistent, severe constipation for over 5 years; she was later found to have an ovarian strumal carcinoid tumor. Computed tomography showed a well-defined solid mass measuring 6.4 cm at the right adnexa. The patient underwent right salpingo-oophorectomy and was histopathologically diagnosed as having a strumal carcinoid tumor. Immunohistochemical examination showed immunoreactivity for peptide YY (PYY), which exerts an inhibitory effect on the peristaltic actions of the distal intestine. After surgery, the patient's constipation resolved rapidly, suggesting a correlation between PYY producing ovarian carcinoid tumor and constipation. This is the first case report of PYY producing primary strumal carcinoid tumor of the ovary associated with persistent, severe constipation from Korea.

키워드

Strumal carcinoid tumor; Peptide YY; Constipation

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