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Rauwolfia에 依한 網膜動脈血壓의 變化

대한안과학회지 1959년 2권 1호 p.45 ~ 49
李相旭 (  ) - 서울대학교 醫科大學

尹源植 (  ) - 서울대학교 醫科大學

Abstract


The diastolic retinal arterial blood pressure was measured by Ophthalmodynamometer in 15 patients of essential hypertension before 2nd after the administration of Raudixin. The patients consisted of 8 males and 7 females, age ranging from 35 to 67 years. The patients were given a single dose-of :iC0 mg. of Raudixin three times a day. The follow up period was 4 to 70 days.
The average fall of the systolic brachial blood pressure was 38.l,mn1Hg (from 174.6 to 136.5 mmPg)1.9 days after the treatment, whereas the average fall of the diastolic brachial blood pressure was 19.6mnm .Hg (from 1.06.5 to e4.7nrHg) 24 days after treatment.
A positive correlation was demonstrated between the retinal and brachial diastolic blood pressures prior to the treatment.
The diastolic brachial blood pressure showed its fall only 15 days after treatment, the average fall being 17.1nan Fg. During this period of time, the average fall of the diastolic retinal arterial pressure was 10.2mmHg.
In 6 cases, the retinal arterial pressure didn´t fall back to the normal values, and in 5 cases of Keith-Wagener group II ,the retinal arterial pressure remained unchanged in spite of the treatment.
The percentage ratio of the retinal to the brachial diastolic blood pressure remained stationary in 3 cases, rose in 4 cases. The number of cases which show fall in this ratio gradually increased and´ about 80%, of the cases demonstrated definite fall one month after treatment.
The retinal arterial pressure remained stationary during 2 weeks after treatment in 60% of the cases The significant lowering of the retinal arterial blood pressure was observed only one month after treatment in the majority of cases. The retinal arterial pressure fell below normal range in no, case.

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