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The Influence of Miotic and Mydriatic Drugs on the Choroidal Blood Flow in Rabbits

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Abstract


The changes in the choroidal blood flow induced by the intravenously administered miotics(pilocarpine, img/kg) and mydriatics(atropine, 0.lmg/kg) were investigated in rabbits with the use of the blood flow measuring apparatus according to the principle of Grayson¢¥s interizal calorimetry, thermistors as sensing elements.
Atropine caused slow increase in the choroidal blood flow after transient decrease, the maximal increase being about 85% of the pre-injection level.
Pilocarpine also produced moderate increase of the blood flow by more than 100%, of the original level.
From these data it is concluded that both atropine and pilocarpine caused significant increase in the choroidal blood flow in rabbit.

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