沃度丁幾燒灼法과 凍結法後의 角膜上皮再生狀態
Comparative Study on the Epithelial Regeneration of the Corneal Ulceration after Cryocautery and Iodine Cautery
韓英洙, 金鍾博, 文幸子,
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韓英洙 ( ) - 서울대학교 醫科大學 眼科學敎室
金鍾博 ( ) - 서울대학교 醫科大學 眼科學敎室
文幸子 ( ) - 서울대학교 醫科大學 眼科學敎室
KMID : 0360219690100030005
Abstract
Recently cryogenic therapy is widely used for the treatment of herpes simplex keratitis. We had experimental studies on the effect of iodine cautery and cryocautery upon the regeneration of corneal ulceration. On 10 adult albino rabbits, one eye was treated by iodine, and the other by cryocautery in area of 0.6cm X 0. 6cm. The epithelium in this area was completely removed by cotton applicator. There after, the rate of epithelial regeneration was observed every 12 hours. The results were as follows:
(1) The average period of -complete epithelial regeneration was 48 hours in animal treated with cryocautery and 78 hours in animals treated with iodine cautery. This difference is statistically highly
significant.
(2) Corneal opacity was not demonstrated in eyes treated with cryocautery. Six eyes treated with iodine, however, showed various degree of corneal opacities.
These results support the view that the healing time in human herpes simplex keratitis is shortened in patients with cryocautery as compared with iodine.
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