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익상편수술후의 Mitomycin 점안요법 Mitomycin Instillation After Pterygium Surgery

대한안과학회지 1971년 12권 4호 p.39 ~ 43
이승훈, 한영수, 서남진, 박춘근,
소속 상세정보
이승훈 (  ) 
서울대학교 의과대학 안과학교실

한영수 (  ) 
서울대학교 의과대학 안과학교실
서남진 (  ) 
서울대학교 의과대학 안과학교실
박춘근 (  ) 
서울대학교 의과대학 안과학교실

Abstract


There have been several methods to prevent the recurrence after pterygium surgery, but no satisfactory method has been brought forth. The value of mitomycin, which appears to offer an important contribution to control the recurrence of pterygium postoperatively, seems to be due to its anticancerous effect. Also it can be used himself easily.
1. We instilled Mitomycin solution after Pterygium surgery to the 85 eyes (77 Patients) visited to the department of Ophthalmology, Seoul National Univ. Hospital from July 1969 to March 1971.
2. Mitomycin solution was instilled three times a day since postoperative first day for one to two weeks. The solution was prepared by solving the Mitomycin-S in the 5cc of distilled water or Mitomycin-C in the 5 cc of physiologic saline solution, so the concentration of solution was 0.4mg per cc.
3. We used bare sclera method in pterygium surgery and all the members of staffs and residents Participated in.
4. Follow-up study was done by direct examinations or questionnaires. The period of the follow-up was at least 6 months to 26 months. We received the answers of 58 eyes, among which 56 eyes (96.6. %) did not recur and only 2 eyes (3.4%) recurred. Of no recurrent cases 42 eyes (75%) were cosmetically satisfactory and 14 eyes (25%) were moderately satisfactory by means of the patients themselves evaluation.
5. Many authors said that the operative technique contributes to the rate of recurrence, so we compared the result of staffs cases with that of residents in 58 eyes. There was no significant difference in the recurrence rate between staffs and residents cases despite of the unskillful techniques of residents.
6. Side effects of Mitomycin solution appeared in 2 eyes one had corneal erosion and edema, another severe conjunclival congestion and chemosis, which disappeared within a few days by ceasing the instillation of mitomycin solution.

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