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소외안근 phosphorylase 활성도에 대한 교감신경효능제 및 봉쇄제의 작용 The effects of adrenergic and adrenergic blocking agents on the phosphorylase activity of bovine extraocular muscles

대한안과학회지 1972년 13권 1호 p.11 ~ 16
박병국,
소속 상세정보
박병국 (  ) 
부산대학교 의과대학 안과학교실

Abstract


The author investigated the effect of adrenergic and adrenergic blocking agents on the phosphorylase activity of bovine extraocular muscle in vitro and obtained the following results:
1. The phosphorylase a activity of bovine extraocular muscle was revealed 5&.6%´ in vitro.
2 The phosphorylase a activity of bovine extraocular muscle was slightly enhanced by the adrenergic agents such as epinephrine, norepinephrine and isoproterenol.
3. The phosphorylase a activity of bovine extr$ocular muscle was not affected -by the adrenergic areceptor blocking agent, phenoxybenzamine but slightly inhibited by the adrenergic (i-receptor blocking agent, propranolol.
4. The phosphorylase a activity of bovine extraocular muscle previously treated with the adrenergic agents was blocked by a sole administration of propranolol or combined administrations of propranolol and phenoxybenzamine but not blocked by phenoxybenzamine alone.

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