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Ginnol이 家兎呼吸에 미치는 影響

Respiratory effect of Ginnol on rabbits

대한약리학잡지 1967년 3권 1호 p.19 ~ 25
이동열,
소속 상세정보
이동열 (  ) - 서울대학교 의과대학 약리학교실

Abstract


Ginnol was obtained from Gingko Biloba L. by purification of its extract.
Author observed the hyperventillation effect on pentobarbital anesthetized rabbit with Ginnol but there was no significant change in blood pressure.
Morphine sulfate, even in large doses, did not alter the hyperventillation effect of Ginnol on rabbit.
Blood chemistry of Ginnol treated rabbit showed slight increase in blood pH but within a physiological normal range, and increased total CO₂ content. While slight decreased pCO₂, increased HCO₃- and decreased H₂CO₃ and with decreased blood Cl- meant an uncompensatory alkalotic change but methemoglobin was not detected.

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