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인삼 Saponin이 백서부고환지방조직에서의 유리지방산동원에 미치는 효과 Effect of Ginseng Saponin on the Mobilization of Free Fatty Acid from Epididymal Fat Pad of Rat

대한약리학잡지 1974년 10권 1호 p.41 ~ 45
박찬웅, 김명석,
소속 상세정보
박찬웅 (  ) 
서울대학교 의과대학 약리학교실

김명석 (  ) 
서울대학교 의과대학 약리학교실

Abstract


The effect of ginseng saponin on the release of free fatty acid from adipose tissue was studied in vitro.
1. The mobilization of free fatty acid from intact epididymal fat pad of rat, incubated in Krebs-Ringer bicarbonate buffer (pH 7.4) contained bovine serum albumin (4 w/v%), was increased by addition of ginseng sponin (1 mg/ml).
2. The mobilization of free fatty acid from homogenate of the epididymal fat pad of rat, of which hormone-sensitive lipese system was activated by pre-incubation of intact fat pad in the presence of epinephrine, was markedly increased by addition of ginseng saponin (0.1~l mg/ml).
3. It is considered that ginseng saponin potentiate the actions of epinephrine on hormone-sensitive lipase system of the adipose tissue of rat.

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