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Φ CalciumúìñøÀÌ ãýøËÔÑ÷¾¿¡ ¹ÌÄ¡´Â ç¯ú¿¡ °üÇÑ æÚϼ CARDIOPULMONARY EFFECTS OF HYPERCALCEMIA

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Abstract


A study was made of cardiopulmonary effects of acute hypercalcemia in mongrel dogs. In this study the dogs were divided into two groups, namely the control and the experimental. In the experimental group, hypercalcemia was induced by the intravenous injection of 10% calcium gluconate, and the cardio functions in this group were compared to those of the control group.
The heart rate was decreased in both the control and the experimental groups, but in the latter there were increases in the cardiac output and the femoral arterial mean pressure and decreases in the total peripheral resistance and the femoral venous pressure compared to those in the control group.
The pulmonary artery mean pressure fell in both groups, but in the experimental group, there was a rather marked elevation in the right ventricular syspressure and some decreases in the right ventricular diastolic pressure and the total pulmonary resistance.
The arterial carbon dioxide tension fell in both groups but the arterial oxygen saturation, the respiratory rate, the tidal volume, the minute ventilation, the oxygen consumption and the carbon dioxide elimination in the experimental group were considerably greater than those in the control group.

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