冷凍手術에 關하여
Some Aspects of Cryosurgery
洪元杓, 金基鈴,
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洪元杓 ( )
延世大學校 醫科大學 耳鼻咽喉科學敎室
金基鈴 ( )
延世大學校 醫科大學 耳鼻咽喉科學敎室
KMID : 0361019730160010067
Abstract
Cryosurgery has been used successfully in treating a great deal of the surgical lesion because it eliminated pain and bleeding in surgical procedures and reduced post operative morbidity since liquid -nitrogen was applieddas cryogen.
The basic mechanism of cryosurgery is that living cells are injured by the effects of freezing. Cell death is brought by a combination of cryobiological effects in addition to simple dehydration, toxic concentration of electrolytes and direct physical effect of ice crystal in intra or extracellular space on the cell membrane. There are also the effect of denaturation of lipoprotein complex and vascular changes including thrombosis.
In 1964, Rand described a cryogenic transsphenoidal hypophysectomy, since then the use of cryosurgery has been described in the labyrinth, neoplasmm of the nasopharynx, laryngeal papilloma, epistaxis and in tonsillectomy.
Rescently, the authors have experienced 13 cases of cryosurgery in E.N.T. field and the results are sufficiently good to encourage continued clinical application.
Additional clinical evaluation of the tecnique is required.
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