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Update on Clinical Manifestation in Acute Low-Tone Hearing Loss

대한이비인후과학회지-두경부외과학 2020년 63권 9호 p.403 ~ 408
김현정, 이호영, 김영찬, 박의현, 최준, 나윤찬, 정학현, 임기정,
소속 상세정보
김현정 ( Kim Hyun-Jung ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
이호영 ( Lee Ho-Young ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
김영찬 ( Kim Young-Chan ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
박의현 ( Park Euy-Hyun ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
최준 ( Choi June ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
나윤찬 ( Rah Yoon-Chan ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
정학현 ( Jung Hak-Hyun ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
임기정 ( Im Gi-Jung ) - Korea University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery

Abstract


Background and Objectives: Acute low-tone hearing loss (ALHL) is gaining attention as an independent disease identity with close association with endolymphatic hydrops and early stage Meniere’s disease (MD). This study aims to compare patients of ALHL with patients exhibiting low-tone hearing loss and ear fullness without vertigo in various audio-vestibular assessments and in progression to overt MD.

Subjects and Method: A total of 249 patients with low-tone hearing loss with ear fullness without vertigo was enrolled in this study. Of these patients, 58 patients met criteria for ALHL, which was defined as having an average hearing loss of ≥30 dB at 125, 250, and 500 Hz and ≤20 dB at 2, 4, and 8 kHz. Demographics, electrocochleography (ECoG) abnormality, rate of hearing improvement, vestibular functions, and progression to MD were analyzed.

Results: An average low-tone hearing loss of ALHL patients was 42.8 dB, which recovered to 18.9 dB following a combined treatment of diuretics and oral steroid therapy. The hearing recovery rate of this group was 87.9% and the ECoG abnormality ratio was 42.5%. Also, 15.5% of ALHL patients eventually progressed to MD.

Conclusion: This study described demographics and characteristics of ALHL, demonstrating a successful response to the combined treatment of diuretics and oral steroid. Also, this report demonstrated a close relationship between the degree of low-tone hearing loss and ECoG abnormality and observed the progression to MD in ALHL patients. These data can be usefully applied in clinical setting to explain clinical outcomes of ALHL.

키워드

Diuretics; Electrocochleography; Hearing loss; Meniere disease; Steroids

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