잠시만 기다려 주세요. 로딩중입니다.

동물 모델에서의 새로운 Brain Infusion Cannula 고정 방법

Novel Tie Method for the Fixation of a Brain Infusion Cannula in a Murine Model

대한이비인후과학회지-두경부외과학 2021년 64권 5호 p.370 ~ 372
문석균, 장문영,
소속 상세정보
문석균 ( Mun Seog-Kyun ) - Chung-Ang University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery
장문영 ( Chang Mun-Young ) - Chung-Ang University College of Medicine Department of Otorhinolaryngology-Head and Neck Surgery

Abstract


Although brain infusion cannula is a good method to deliver compounds directly into thebrain, fixation of the brain infusion cannula is essential for successful delivery. Dental cementsand adhesive gel are the commonly used materials for fixation of the infusion cannula.
However, these materials take time to harden and occasionally, fixation may fail. Therefore,we developed a novel method to fix the brain infusion cannula. Brain infusion cannulas wereimplanted into seven Wistar rats using the novel tie method. One, three, and seven days afterthe surgery, displacement of the brain infusion cannula and cerebrospinal fluid (CSF) leakagewere evaluated in all the rats. None of the animals showed displacement of the brain infusioncannula or leakage of CSF at any point of time. In this study, we showed the successful resultsof the novel tie method for fixation of the brain infusion cannula, which needs no additionalmaterials. It only requires a thread which is used for skin sutures.

키워드

Brain; Cannula; Cerebrospinal fluid

원문 및 링크아웃 정보

등재저널 정보