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齒根端肉芽腫의 病理組織學的 및 組織化學的 硏究

HISTOPATHOLOGICAL AND HISTOCHEMICAL STUDIES ON THE DENTAL GRANULOMAS

대한치과의사협회지 1970년 8권 12호 p.665 ~ 672
신무수,
소속 상세정보
신무수 (  ) - 서울대학교 대학원 구강병리학전공

Abstract


The author has studied histopathologically and histochemically on the 50 cases of dental granulomas which had been collected from the April, 1970 to October, 1970.
The results are as follows:
1. In 50 cases of Dental Granulomas, 26 cases (52. 0%) showed epithelial proliferation, which were composed of 25 cases (96.15%) of squamous epithelium and 1 case (3.85%) ciliated epithelium.
2. In the 26 cases.of epitheliated granulomas, precystic appearances showed in 6 cases (23.08%), mild calcification in central portion of the epithelium in 2 cases (7. 69%), and mild hyalinization in central portion of the, epithelium in 3 cases (11. 54%).
3. Histopathological view of the 50 dental granulomas, small abscess cavities were appeared in 4 cases (8.0%), sclerosed granuloma in 1 case (2.0%), cholesterol clefts in 1 case (2.0%), giant cells in 7 cases (14.0%), moderate foam cell infiltration in 7 cases (14.0%), new bone formatioii in 5 cases (10. 0%), calcified masses in peripheral portion of the granulation tissue in 4 cases (8.0%), and Russell´s fuchsin bodies were appeared in all cases (100%).
4. The Mucicarmine reaction on the epithelial islands in granulation tissue was reacted negatively.
5. The degree of PAS reaction on the epithelium revealed irregular and weakened tendency compared with normal gingival epithelium, but the reaction of connective tissue flbers showed similar to the lamina propria of the normal gingiva. And the degree of PAS reaction was decreased with severity of inflammatory reaction.
6. The Alcian Blue reaction on the connective tissue fibers was similar to the PAS reaction, but the epithelium was reacted lightly or negatively, and especially the connective tissue fibers of closed adjacent to epithelium were reacted intensively.

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