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항암제투여가 가토치수에 미치는 영향에 관한 실험적 연구 THE STUDY ON THE EFFECTS OF THE NITROGEN MUSTARD TO THE DENTAL PULPS OF RABBITS

대한치과의사협회지 1977년 15권 7호 p.517 ~ 519
김용화,
소속 상세정보
김용화 ( Kim Yong-Hwa ) 
서울대학교 대학원 치의학과 구강외과학

Abstract


The author studied the effects of cyclophosphamide to the Dental pulps of Rabbits. Eighteen rabbits were used. The experimental rabbits were given an intramuscular injection of cyclophosphamide 50mg. per 1.5Kg. of body weight. In order to investigate effects of cyclophosphamide to the pulps of rabbits the control and experimental rabbits were sacrificed, on 1,3,5,7,10, and 14 days after injection of cyclophosphamide and made preparations for histopathologic findings. The results were as fallows. 1. In the early stage after injection of cyclophosphamide, retrcgrade degeneration of pulps such as infiltration of inflammatory cells, vacuolization, hyaline degeneration and reticular tissue atrophy in pulps were revealed. 2. The pulps were recovered from 10 to 14 days after injection of cyclophosphamide.

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