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Cantharidin에 의한 각종(各種) 우췌 및 박염성연속종(博染性軟屬腫)에 대한 구소도포요법

Topical Treatment of Verrucae and Molluscum Contagiosum with Cantharidin

대한피부과학회지 1970년 8권 2호 p.37 ~ 40
이정복, 박욱화, 우준식, 우태하,
소속 상세정보
이정복 ( Lee Jung-Bock ) - 연세대학교 의과대학 피부과학교실
박욱화 ( Bark Wook-Hwa ) - 연세대학교 의과대학 피부과학교실
우준식 ( Woo Joon-Sik ) - 연세대학교 의과대학 피부과학교실
우태하 ( Woo Tae-Ha ) - 연세대학교 의과대학 피부과학교실

Abstract


he pathologic change: of verrucae and molluscum. contagiosum are limitted chiefly to epidermis, therefore treatment with cantharidin which forms acantholytic bulla is successful.
Canthrides is dried, powdered blister beetle, and cantharidin is its purified active ingredient. Its primary cutaneous effect is acantholy sis and death of epidermal cells. For topical treatment, catharidin was prepared as a 0.9% solution in mixture of 50% of acetone, 25% of ether and 25% flexible collodion U.S.P.
The therapeutic efficacy of cantharidin was excellent to eliminate the lesions of verrucae and molluscum contagiosum, showing the complete recovery of 114 out of 117 lesions of verrucae and 520 out of 550 lesions of molluscum contagiosum with 1 to 3 topical applications.
From the above results, it should be pointed out that cantharidin has the several advantages at clinical uses for the treatment of verrucae and molluscum contagiosum: 1. No residual scarring. 2. No pain. 3. Excellent therapeutic efficacy.

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