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전신 및 국소마취하(局所痲醉下) 기계자극이 백서피부조직(白鼠皮膚組織) 비반 세포변형에 미치는 영향에 관한 실험적 연구 Experimental Study on Tissue Mast Cell Change of Ratskin Elicited by Mechanical Irritation Under General and Local Anesthesia

대한피부과학회지 1972년 10권 1호 p.11 ~ 22
유태연, 김홍식,
소속 상세정보
유태연 ( Yoo Tae-Yun ) 
서울대학교 의과대학 피부과학교실

김홍식 ( Kim Hong-Sig ) 
서울대학교 의과대학 피부과학교실

Abstract


Normal albino rats weighing 180-200 gm were used for a series of this investigation on change of skin mast cell under general and local anesthesia. At first, left side abdominal skin was prepared by hair cutting with scissors about 3cm square and eight irritations by mean of biting with tip of forceps mosquito were applied along the prepared skin margin. Skin specimens were submitted from central area which surrounded by irritated points and also from intact contra-lateral area in 15, 30, 60 and 120 minutes invervals. Submitted skin specimens were fixed in 10% formalin solution, then were stained with 1% toluidine blue. The number of mast cell was counted under 45OX of microscopic examination.

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