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Descresept^® 投與가 아토피性 皮膚炎患者의 臨床經過 및 白血球貪食 作用에 미치는 影響 Influence of Descresept^® on Clinical Course and Phagocytic Function of Neutrophils in Atopic Dermatitis

대한피부과학회지 1974년 12권 4호 p.233 ~ 236
孫淑子, 孫敬愛,
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孫淑子 (  ) 
國立醫療院 皮膚科

孫敬愛 (  ) 
國立醫療院 皮膚科

Abstract


The study was undertaken to evaluate the phagocytic function of polymorphonuclear leukocyte correlated with clinical appearance following Descresept^(®)(aristolochic acid) administration in 11 patients with atopic dermatitis.
Nitroblue tetrazolium dye reduction test was done as weekly interval, including before and after oral Descresept^(®) and the method was essentially same with that of original Park et al. The results are as follows.
1. In 6 of 11 patients, clinical improvement was accompanied by increasing NBT scores. The clinical improvement was first noted in about 1 week after starting of oral Descresepe^(®).
2. In 2 of 11 patients, clinical aggravation was noted inspite of Descresept administration. Increase in dosage of Descresept^(®) made clinical improvement with increasing NBT scores.
3. In 3 of the 11 patients, there was clinical improvement, but NBT scores weres slightly decreased.

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