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비결핵성 항산균과 연관된 유육종증 1예

A Case of Sarcoidosis Associated with Non-tuberculous Mycobacteria

대한피부과학회지 2020년 58권 7호 p.483 ~ 486
석승휘, 신정우, 김현정, 이희정, 윤문수, 김동현,
소속 상세정보
석승휘 ( Seok Seung-Hui ) - CHA University CHA Bundang Medical Center Department of Dermatology
신정우 ( Shin Jung-U ) - CHA University CHA Bundang Medical Center Department of Dermatology
김현정 ( Kim Hyun-Jung ) - CHA University CHA Bundang Medical Center Department of Dermatology
이희정 ( Lee Hee-Jung ) - CHA University CHA Bundang Medical Center Department of Dermatology
윤문수 ( Yoon Moon-Soo ) - CHA University CHA Bundang Medical Center Department of Dermatology
김동현 ( Kim Dong-Hyun ) - CHA University CHA Bundang Medical Center Department of Dermatology

Abstract


Sarcoidosis is a multisystem granulomatous disease of unknown etiology. A range of factors including tuberculous infection, beryllium exposure, and cold climate have been implicated in the pathogenesis of the condition. A 45-year-old woman presented with a 4-month history of an asymptomatic eyelid swelling and multiple erythematous papules on the neck. Histological examination of the neck, orbital soft tissue, and lacrimal gland was consistent with sarcoidosis. Ziehl?Neelsen stains and polymerase chain reactions (PCRs) for tuberculosis on the skin biopsy specimens were negative. However, the orbital soft tissue specimen was positive for non-tuberculous mycobacteria (NTM) PCR. The patient was finally diagnosed with sarcoidosis associated with NTM. Treatment with systemic steroid and hydroxychloroquine was started, resulting in an improvement of skin lesions. We herein report a case of sarcoidosis associated with NTM infection with review of the literature, as only little is known regarding the role of mycobacteria in sarcoidosis.

키워드

Non-tuberculous mycobacteria infection; NTM infection; Sarcoidosis

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