잠시만 기다려 주세요. 로딩중입니다.

만성피로증후군의 증상관리를 위한 추나요법의 유용성: 체계적인 문헌고찰과 메타분석

Benefit of chuna for managing symptoms in chronic fatigue syndrome patients: A systematic review and meta-analysis

대한한의학회지 2020년 41권 3호 p.205 ~ 220
송정윤, 김준열, 남동현,
소속 상세정보
송정윤 ( Song Jeong-Yun ) - Sangji University College of Korean Medicine Department of Biofunctional Medicine and Diagnosis
김준열 ( Kim Jun-Yeol ) - Sangji University College of Korean Medicine Department of Biofunctional Medicine and Diagnosis
남동현 ( Nam Dong-Hyun ) - Sangji University College of Korean Medicine Department of Biofunctional Medicine and Diagnosis

Abstract


Objectives: The aim of this review is to assess the clinical benefit of chuna for managing symptoms in chronic fatigue syndrome (CFS)

Methods: We searched eligible studies from the following 11 databases with no language restriction: Pubmed, CENTRAL, Embase, CNKI, CQVIP, Wanfang, CiNii, OASIS, RISS and Koreamed. We selected randomized controlled trial (RCT), quasi-randomized controlled trial (Quasi-RCT) and controlled clinical trial (CCT) in which patients with chronic fatigue syndrome were treated with chuna. The results of the included studies were synthesized through meta-analysis, and their risk of bias were also assessed.

Results: We searched 914 potentially relevant studies, and only 20 studies were selected for this systematic review. Meta-analysis showed that chuna was more effective in improving general symptoms (n=291, RR 0.19 [95% CI 0.11 to 0.32], Z=6.08, p<0.00001, I2=0%), fatigue (n=487, SMD ?0.95 [95% CI ?1.19 to ?0.71], Z=7.76, p<0.00001, I2=37%) and sleep disorder (n=139, SMD ?0.58 [95% CI ?0.92 to ?0.24], Z=3.36, p=0.0008, I2=0%) compared to health supplements or usual care. When chuna was used as an added intervention, it was more effective in improving general symptoms(n=729, RR 0.25 [95% CI 0.15 to 0.42], Z=5.19, p<0.00001, I2=0%) and fatigue severity alone(n=217, SMD ?1.21 [95% CI ?1.53 to ?0.89], Z=7.45, p<0.00001, I2=15%) compared to control.

Conclusion: We found that chuna was beneficial for improving severity of general symptoms and fatigue at post treatment in CFS patients.

키워드

Tuina; Chuna; Chronic fatigue syndrome; Meta-analysis; Systematic review

원문 및 링크아웃 정보

 

등재저널 정보