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코로나-19 무증상 감염 환자의 한약 치료 방안에 대한 고찰

A review on the treatment of Herbal Medicine for asymptomatically infected COVID-19 patients

대한한의학회지 2021년 42권 1호 p.99 ~ 109
정선형, 이경은, 정민정, 송미덕, 장인수,
소속 상세정보
정선형 ( Jeong Seon-Hyung ) - Woosuk University College of Korean Medicine Department of Korean Medicine
이경은 ( Lee Kyoung-Eun ) - Woosuk University College of Korean Medicine Department of Korean Medicine
정민정 ( Jeong Min-Jeong ) - Woosuk University College of Korean Medicine Department of Pediatrics
송미덕 (  ) - Kyunghee Oriental Medical Clinic
장인수 ( Jang In-Soo ) - Woosuk University College of Korean Medicine Department of Internal Medicine

Abstract


Objectives: Objective: The purpose of this study is to investigate the treatment of herbal medicine for patients with COVID-19 asymptomatic infections.

Method: In English, search engines such as ‘PubMed’, ‘Science Direct’, and ‘Cumulative Index to Nursing and Allied Health Literature (CINAHL)’ were used. In Chinese, search engines such as ‘China National Knowledge Infrastructure (CNKI)’ and Wanfang were used. The keywords for the search engines were ‘COVID-19’, ‘asymptomatic infection’, ‘Korean Medicine’, ‘traditional Chinese medicine’, ‘herbal medicine’, and etc. Only clinical studies using herbal medicine for patients without fever or respiratory symptoms were selected. We excluded the cases that do not fit the research topic.

Results: A total of 5 studies were finally selected. Among them, four of them used integrated herbal medicine and Western medicine, and one of the studies treated exclusively for herbal medicine. There were a total of seven prescriptions for herbal medicine used in the study. Outcome variables were used as following: lab test, nucleic acid conversion time, hospitalization period, chest CT, and etc. In the RCT study, herbal medicine and Western medicine decreased nucleic acid conversion time, average hospitalization time compared to the control group, but it was not statistically significant. No other adverse reactions were reported in all studies.

Conclusion: According to the results, integrated herbal medicine and Western medicine might be an effective treatment for patients with COVID-19 asymptomatic infection reducing hospitalization period, time of nucleic acid turning negative. No severe adverse effects were reported. However, it is thought that better-designed research will be needed in the future.

키워드

COVID-19; asymptomatic infection; herbal medicine; Korean medicine

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