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各種肺疾患에서의 Pulmonary Surfactant 에 對해서 Surface Activity in Various Pulmonary Diseases

대한흉부외과학회지 1972년 5권 1호 p.1 ~ 7
林炳和, 金珍植, 申根洙,
소속 상세정보
林炳和 (  ) 
釜山大學校 胸部外科

金珍植 (  ) 
釜山大學校 胸部外科
申根洙 (  ) 
釜山大學校 胸部外科

Abstract


0n the study of surface activity in excized lung extracts of various pulmonary diseases, following facts were concluced.
1) The minimum suface tension measured in lung extracts of tuberculous tissue surrounding cavitary lesson was 26.3 dyne/cm and its stability index was 0.53.
2) Macroscopically almost normal lung tissue at a distance of tuberculous lesion in same lobe revealed 21.3 dyne/cm of minimum surface tension in extracts and its stability index showed 0.66. This low surface activity may be due to the chronic pneumonitis microscopically.
3) In the atelectatic lung which had been collapsed by chronic emyema the extracts revealed much higher minimum surface tension in 27.3 dyne/cm and its stability index revealed the least value of 0.47 without correlation of duration of disease.
This suggests that the longstanding collapsed lung may be soon collapsed even after mechanical full expansion because of lack of surfactant. surfactant.

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