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뇌하수체 적출 토끼의 철 대사에 관한 연구

Studies on Iron Metabolism in the Hypophysectomized Rabbit

부산의대잡지 1969년 9권 1호 p.57 ~ 71
김광덕,
소속 상세정보
김광덕 (  ) - 부산대학교 대학원 의학과

Abstract


The author observed, the changes in plasma iron concentration in the rabbits undergone hypophysectomy, in the rabbits hypophysectomized and made anemic by a removal of massive blood cells, administered with or without iron enterally, and furthermore in the rabbits hypophysectomized and given colloidal iron intravenously. The results thus obtained were discussed and arrived at the following conclusions:
1. The plasma iron concentration decreased progressively following the hypophysectomy to reach a definite level.
2. The decrease of plasma iron concentration following the removal of the blood cells in the hypophysectomized rabbits was milder in degree than in the intact rabbits.
3. There seemed to be no abnormality in the iron absorption through. the intestine in the hypophysectomized rabbits.
4. The hypophysectomized rabbits seemed to accumulate the iron given parentrally as well as the intact ones, but to release the over-stored iron more rapidly than the latter.
5. It was suggested that the difference in iron metabolism between the hypophysectomized rabbits and the intact ones might be not a qualitative, but a quantitative one.

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