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¹éÇ÷±¸ Áõ°¡Áõ ȯÀÚ¿¡À־ ¹éÇ÷±¸ Alkaline Phosphatase Ȱ¼º¿¡ °üÇÑ Á¶Á÷È­ÇÐÀû ¿¬±¸ A Histochemical Study on Leukocyte Alkaline Phosphatase Activitics in Patients with Leukocytosis

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Abstract

ÀúÀÚ´Â °Ç°­ÀÎ 35¿¹¿Í ¹éÇ÷±¸ Áõ°¡Áõ ȯÀÚ 90¿¹¸¦ ´ë»óÀ¸·Î ÇÏ¿© ¼øÈ¯ Ç÷¾×ÀÇ ¹éÇ÷±¸ÀÇ AP Ȱ¼ºÀ» °üÂûÇϰí, ±× ¼º°ÝÀ» À§¿¡¼­ °í¾ÈÇÑ ¹Ù¿¡ ÀǰÅÇÏ¿© ´ÙÀ½°ú °°ÀÌ ¿ä¾àÇÑ´Ù.
1. ¹éÇ÷±¸ Áõ°¡Áõ ȯÀڵ鿡 À־´Â ¹éÇ÷±¸ÀÇ AP Ȱ¼ºÀº Áõ°¡µÇ¾ú´Ù.
2. È£Áß±¸ Áõ°¡ÁõÀ» ¼ö¹ÝÇÏÁö ¾Æ´ÏÇÑ ¹éÇ÷±¸ Áõ°¡Áõ ȯÀÚ¿¡ À־´Â ¹éÇ÷±¸ÀÇ AP Ȱ¼ºÀº Áõ°¡µÇÁö ¾Æ´ÏÇÏ¿´À¸¸ç, À̰ÍÀ» ¼ö¹ÝÇÑ ¹éÇ÷±¸ Áõ°¡Áõ ȯÀÚ¿¡ À־´Â ¹éÇ÷±¸ÀÇ AP Ȱ¼ºÀº Áõ°¡ÇÏ¿´´Ù.
3. È£Áß±¸ Áõ°¡ÁõÀÌ ½ÉÇÑ È¯ÀÚÀ̼ö·Ï ¹éÇ÷±¸ AP Ȱ¼ºÀÌ ´õ °­ÇÏ¿´´Ù.
In an attempt to elucidate the mechanism for the increase of alkaline phosphatase(abbreviated as AP) activities of leukocytes in the patients with leukocytosis, the author investigated AP activities of neutro¡©phi es, with the Tomonaga¢¥s naphthol AS-MX phosphate method, in 90 cases of the mate patients with leukocytosis and in 35 cases of the healthy adult males. The results of this study were discussed and were summarized as follows:
Leukocyte Ap activity increased remarkably in the patients with leukocytosis. The increase was found only in the patients with leukocytosis characterized by neutrophilia and it was almost parallel with the increase of circulating neutrophil count.

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