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Abstract

ÀúÀÚ´Â ºÎ»êÁö¹æ Çѱ¹Àο¡ ¹ß»ýÇÑ 155¿¹ÀÇ ¿ø¹ß¼º °£¾ÏÀ» ´ë»óÀ¸·Î ÇÏ¿© Åë°èÇÐÀû ¹× º´¸®Á¶Á÷ÇÐÁ¤ ¹æ¹ý¿¡ ÀÇÇÏ¿© °£¾Ï°ú °£µð½ºÅ丶ÁõÀÇ °ü°è¸¦ Á¶»çÇÏ¿´´Ù. ÀúÀÚ´Â ÀÌ Á¶»ç¿¡ ÀÇÇÏ¿© ¾òÀº ¼ºÀûÀ» À§¿¡¼­ °í¾ÈÇϰí, ´ÙÀ½°ú °°ÀÌ ¿ä¾àÄÚÀÚ ÇÑ´Ù.
1) ºÎ»êÁö¹æ¿¡ °ÅÁÖÇÏ´Â Çѱ¹Àε鿡¼­ ¹ß°ßµÈ ¿ø¹ß¼º °£¾ÏÁß ´ã°ü»óÇǼº °£¾ÏÀº 19.4%À̾úÀ¸¸ç, °£¼¼Æ÷¼º °£¾ÏÀº 80.6%¿´´Ù. ÀÌ Áö¹æ Áֹο¡ À־ ´ã°ü»óÇǼº °£¾ÏÀÇ ¹ß»ýÀ²Àº ¾ÆÇÁ¸®Ä« ¿øÁÖ¹Î, ¹Ì±¹ ¹éÀÎ ¹× ÀϺ»Àε鿡 À־ º¸´Ù ³ô¾Ò´Ù.
2) ´ã°ü»óÇǼº °£¾Ï¿¡ À־´Â µð½ºÅ丶¼º °£°æ·ÃÁõÀ» ÇÕº´ÇÏ´Â À²ÀÌ ¶Ñ·ÇÀÌ ³ô¾Ò°í, °£¼¼Æ÷¼º °£¾Ï¿¡ À־´Â ºñµð½ºÅ丶¼º °£°æº¯ÁõÀ» ÇÕº´ÇÏ´Â À²ÀÌ ¸Å¿ì ³ô¾Ò´Ù.
3) µð½ºÅ丶¼º °£°æº¯ÁõÀ» ÇÕº´ÇÑ ´ã°ü»óÇǼº °£¾Ïµé¿¡¼­´Â Áõ½ÄÇÑ ´ã°ü»óÇÇ ¼¼Æ÷°¡ ¾Ï¼¼Æ÷·Î ÀÌÇàÇÏ´Â º¯È­¶ó°í ÀνĵǴ Á¶Á÷ÇÐÀû ¼Ò°ßÀ» ³ªÅ¸³Â´Ù.
4) µð½ºÅ丶¼º °£°æº¯ÁõÀ» ÇÕº´ÇÑ ´ã°ü»óÇǼº °£¾ÏÀº 50´ë¿¡ ºó¹ßÇÏ¿´°í, ¿©ÀÚº¸´Ù ³²ÀÚ¿¡ ´õ ¸¹ÀÌ ¹ß»ýÇÏ¿´´Ù.
5) µð½ºÅ丶¼º °£°æº¯ÁõÀ» ÇÕº´ÇÑ ´ã°ü»óÇǼº °£¾ÏÀÇ °£±â´É °Ë»çÁ¶°ß°ú ´Ù¸¥ÇüÀÇ ¿ø¹ß¼º °£¾ÏÀÇ °£±â´É °Ë»ç¼Ò°ß »çÀÌ¿¡ Ư±âÇÒ¸¸ÇÑ »ç½ÇÀ» ¹ß°ßÇÏÁö ¸øÇÏ¿´´Ù.
ÀúÀÚ´Â »ó±âÇÑ ¹Ù¿¡ ÀǰÅÇÏ¿© °£µð½ºÅ丶´Â ´ã°ü»óÇǼº °£¾ÏÀÇ ¿øÀÎÀû ÀÎÀÚ¶ó´Â ¼³¿¡ µ¿Á¶ÇÏ´Â µ¿½Ã¿¡ ºÎ»êÁö¹æ¿¡ ÀÌ·±ÇüÀÇ ¾ÏÀÌ ¸¹Àº°ÍÀº Áö¹æ dzÅ亴ÀÇ ÇϳªÀÎ °£µð½ºÅ丶Áõ¿¡ ±âÀÎÇÑ´Ù°í °­Á¶ÇÏ´Â ¹ÙÀÌ´Ù.
To trace the relation between liver carcinoma and clonorchiasis an analytical observation was made on 155 cases of frintary liver carcinoma which were subjected to pathological evaluation in our department o =pathology during the years from 1965 to 1973. The diagnosis was established by gross observation at opetation table and morphological examination of the liver biopsy. The cases were analyzed statistically and histologically, and obtained results that could by summarized as follows:
1. OFthe 155 cases of primary liver carcinoma 30 cases(19. 4%) were bile duct carcinoma and 125 cases (80.6%) liver cell carcinoma. The incidence of bile duct carcinoma was higher in the inhabitants in Busan area than in American white, Negros in Africa, and Japanese.
2 In the group dbile duct carcinoma the rate of complication of parasitic cirrhosis was exeedingly high, while in the group of liver cell carcinoma the rate of complication of non-parasitic cirrhosis was very high.
3. In the bile duct carcinomas with parasitic cirrhosis there were noted histological changes which could be interpreted as a transformation of hyperplastic bile duct` epithelium into malignant cells.
4. The incidence of bile duct carcinoma with parasitic cirrhosis was higher in male than in female, and was highest in 5th decade.
5. In the findings of liver function tests there was no distinct difference between the cases of bile duct carcinoma with parasitic cirrhosis and those of other types of primary liver carcinoma.
From the above results the auther supports the theory that Clonorchis sinensis may be a causative factor of bile duct carcinoma, and emphasizes that the high incidence of this type of carcinoma in-Busan area is due. to donorchiasis widely prevalent there.

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