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腸티푸스의 臨床的 觀察 Clinical Studies on 116 Cases of Typhoid Fever

부산의대잡지 1977년 17권 2호 p.125 ~ 130
신영기,
소속 상세정보
신영기 (  ) 
부산대학교 의과대학 내과학교실

Abstract


Clinical studies were carried out on the 116 cases of typhoid fever patients treated in the Busan National University Hospital during last 4 years and 10 months, and the following results were obtained.
1. Seasonal prevalence was similar but slightly prominent in summer. The ratio between male and female was 1:1.2. Most cases (45. 7%) were found in 21-30 age group, and 64.6% of total patients visited the hospital within 2 weeks after the onset of the disease.
2. The most common symptoms were fever(85.3%), chill(74. 1%), headache(64.7%), anorexia (595%), general aching (51.7%) and coughing (41. 4%) in that order of frequency. Important physical signs were abdominal tenderness(75.9%), coated tongue(63.8%) splenomegaly(55.2%), hepatomegaly(37.9%) and relative bradycardia(25. 0%).
3. Peripheral blood findings showed leukopenia in 49. 1% and leukocytosis 3. 4% of the cases.
4. Results of liver function tests were as follows: positive C. C. F. in 4.3%, positive T. T. T. in 14. 7%, elevated G. O. T and G. P. T. in 68.1% and 49. 1% respectively.
5. Widal reaction was positive in 83 patients(71.6%) of 116 and 17 patients of 28 who were 1:80 titer on initial examination showed 1:160 titer after 1 week.
6. Of the 36 patients who received blood culture, Salmonella Typhosa were isolated in 23(63. 9%),
however, of 92 patients who received stool culture, the organisms were isolated in 29 (31. 5%).
7. The complications were found in 26.7% of total cases and the most common complications were intestinal hemorrhage(19. 0%), intestinal perforation(2. 6%), meningitis(1.7%), pneumonia(1.7%), cholecystitis(0.9%) and renal failure(0.9%).
8. Two patients were admitted with complaining of meningeal signs.
9. Clinically favorable response was obtained in the first group treated with 3 Gm CM daily and less favorable in the second group treated 2Gm CM daily. In the first group defeverescence was obtained average in 4. 5 days and the second group in 6 days.

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