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1958年度에 流行한 <디프테리아>의 臨床的 觀察

CLINICAL OBSERVATION ON THE DIPHTHERIA DURING 1958∼1959

소아과 1962년 3권 1호 p.52 ~ 57
소속 상세정보
桂姬淑/Koh, Hee Sook 韓鏞徹/Han, Yong Chul

Abstract


The clinical observation on 85 cases of diphtheria under 15 years of age who were admitted to Seoul University hospital during 1958?1959 are reviewed, and the results are as follows.
1. Among 85 cases, male was 60 and female was 25, and the most of the cases were under 7
years of age. The mortality rate was 5.9%.
2. The occurrence of diphtheria was highest during winter (Dec., Nov., Jan., Feb.) but rare, in from July to September.
3. Type of diphtheria was devided into pharyngeal, laryngeal, nasal, Iaryngophary:igeal, nasopharyngeal and nasolaryngo pharyngeal type on the basis of clinical findings. Among, these types, the pharyngeal occupiert the majority of the cases and the Iaryngopharyngeal, the Iaryngeal was next in order.
4. Fever was noted in 89.4% dyspnea in 51.8% and cervical lymphnode swelling in 16.5% of the cases.
5. Tonic myocarditis was seen in 3 cases, of whom 2 patients died, and sinus arrhythmia in 5 cases and pneumonia in 2 cases as complication.
6. Serum sickness was seen in only one case.
7. 5 cases in whom sensitivity test was done, diphtheria bacilli were sensitive to the most of antibiotics but 4 cases out of 5 were proved to be moderate sensitive to penicillin and streptomycin.
8. Tracheotomy was performed on 20 patients (23.5%), two deaths out of these 20 patients.
9. In all cases diphtheria antitoxin was given. Antitoxin was combined Nvith antibiotics in 76 cases.
There ..as no difference in rapidity of disappearance of diphtheria bacilli from the lesion between the group treated with antitoxin penicillin and that treated with antitoxin erytlsomycin. In most of cases diphtheria bacilli disappeared within 5 days by the smear and culture (68.0%, 76.5%).

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